TY  - JOUR
PY  - 2018//
TI  - Acute stress disrupts temporal patterns of behavioral and biochemical parameters of rats
JO  - Biological rhythm research
A1  - Souza, Andressa
A1  - Detanico, Bernardo Carraro
A1  - Medeiros, Liciane Fernandes
A1  - Oliveira, Carla de
A1  - Scarabelot, Vanessa Leal
A1  - Cioato, Stefania Giotti
A1  - Caumo, Wolnei
A1  - Torres, Iraci LS
SP  - 521
EP  - 538
VL  - 49
IS  - 4
N2  - This study aimed to answer these questions: (i) Can the temporal patterns of locomotor and exploratory activities and anxiety-like behavior be disrupted by a single session of stress? (ii) Can the temporal patterns of corticosterone, melatonin, and glucose be disrupted by a single session of stress and how long does the effect of stress upon their circadian rhythm? Adult male Wistar rats were exposed to restrain stress at four Zeitgeber Times and subdivided according to evaluation times of behavioral (open field test and elevated plus-maze test) and biochemistry (corticosterone, melatonin, and glucose levels in serum) parameters. There were temporal patterns within a course of 24 h in anxiety-like behaviors and glucose levels. Circadian rhythm to corticosterone and melatonin levels was confirmed and a single session of stress can disrupt these temporal patterns. We showed an immediate disruptive effect of stress in biomarkers levels and a delayed appearance of behavioral and locomotion pattern disruption.<p />  <p>Language: en</p>
LA  - en
SN  - 0929-1016
UR  - http://dx.doi.org/10.1080/09291016.2017.1386267
ID  - ref1
ER  -