TY  - JOUR
PY  - 2019//
TI  - The concise health risk tracking-self report: psychometrics within a placebo-controlled antidepressant trial among depressed outpatients
JO  - Journal of psychopharmacology
A1  - Trombello, Joseph M.
A1  - Killian, Michael O.
A1  - Grannemann, Bruce D.
A1  - Rush, Augustus John
A1  - Mayes, Taryn L.
A1  - Parsey, Ramin V.
A1  - McInnis, Melvin
A1  - Jha, Manish K.
A1  - Ali, Aasia
A1  - McGrath, Patrick J.
A1  - Adams, Phil
A1  - Oquendo, Maria A.
A1  - Weissman, Myrna M.
A1  - Carmody, Thomas J.
A1  - Trivedi, Madhukar H.
SP  - 185
EP  - 193
VL  - 33
IS  - 2
N2  - BACKGROUND/AIMS:: While substantial prior research has evaluated the psychometric properties of the 12-item Concise Health Risk Tracking-Self Report (CHRT-SR<sub>12</sub>), a measure of suicide propensity and suicidal thoughts, no prior research has investigated its factor structure, sensitivity to change over time, and other psychometric properties in a placebo-controlled trial of antidepressant medication, nor determined whether symptoms change throughout treatment. <br><br>METHODS:: Participants in the multi-site Establishing Moderators and Biosignatures of Antidepressant Response in Clinical Care (EMBARC) study ( n=278) provided data to evaluate the factor structure and sensitivity to change over time of the CHRT-SR<sub>12</sub> through eight weeks of a clinical trial in which participants received either placebo or antidepressant medication (sertraline). <br><br>RESULTS/OUTCOMES:: Factor analysis confirmed two factors: propensity (comprised of first-order factors including pessimism, helplessness, social support, and despair) and suicidal thoughts. Internal consistency (α's ranged from 0.69-0.92) and external validity were both acceptable, with the total score and propensity factor scores significantly correlated with total scores and single-item suicidal-thoughts scores on the self-report Quick Inventory of Depressive Symptoms and the clinician-rated 17-item Hamilton Rating Scale for Depression. Through analyzing CHRT-SR<sub>12</sub> changes over eight treatment weeks, the total score and both the factors decreased regardless of baseline suicidal thoughts. Change in clinician-rated suicidal thoughts was reflected by change in both the total score and propensity factor score. <br><br>CONCLUSIONS/INTERPRETATION:: These results confirm the reliability, validity, and applicability of the CHRT-SR<sub>12</sub> to a placebo-controlled clinical trial of depressed outpatients receiving antidepressant medication.<p />  <p>Language: en</p>
LA  - en
SN  - 0269-8811
UR  - http://dx.doi.org/10.1177/0269881118817156
ID  - ref1
ER  -