TY - JOUR
PY - 2019//
TI - Nutritional status, body mass index, and the risk of falls in community-dwelling older adults: a systematic review and meta-analysis
JO - Journal of the American Medical Directors Association
A1 - Trevisan, Caterina
A1 - Crippa, Alessio
A1 - Ek, Stina
A1 - Welmer, Anna-Karin
A1 - Sergi, Giuseppe
A1 - Maggi, Stefania
A1 - Manzato, Enzo
A1 - Bea, Jennifer W.
A1 - Cauley, Jane A.
A1 - Decullier, Evelyne
A1 - Hirani, Vasant
A1 - LaMonte, Michael J.
A1 - Lewis, Cora E.
A1 - Schott, Anne-Marie
A1 - Orsini, Nicola
A1 - Rizzuto, Debora
SP - 569
EP - 582.e7
VL - 20
IS - 5
N2 - OBJECTIVES: To evaluate the association between nutritional status, defined on the basis of a multidimensional evaluation, and body mass index (BMI) with the risk of falls and recurrent falls in community-dwelling older people.
DESIGN: Systematic literature review and meta-analysis. SETTING AND PARTICIPANTS: Community-dwelling older adults. MEASURES: A systematic literature review was conducted on prospective studies identified through electronic and hand searches until October 2017. A random effects meta-analysis was used to evaluate the relative risk (RR) of experiencing falls and recurrent falls (≥2 falls within at least 6 months) on the basis of nutritional status, defined by multidimensional scores. A random effects dose-response meta-analysis was used to evaluate the association between BMI and the risk of falls and recurrent falls.
RESULTS: People who were malnourished or those at risk for malnutrition had a pooled 45% higher risk of experiencing at least 1 fall than were those well-nourished (9510 subjects). Increased falls risk was observed in subjects malnourished versus well-nourished [RR 1.64, 95% confidence interval (CI) 1.18-2.28; 3 studies, 8379 subjects], whereas no substantial results were observed for risk of recurrent falls. A U-shaped association was detected between BMI and the risk for falls (P < .001), with the nadir between 24.5 and 30 (144,934 subjects). Taking a BMI of 23.5 as reference, the pooled RR of falling ranged between 1.09 (95% CI 1.04-1.15) for a BMI of 17, to 1.07 (95% CI 0.92-1.24) for a BMI of 37.5. No associations were observed between BMI and recurrent falls (120,185 subjects).
CONCLUSIONS/IMPLICATIONS: The results of our work suggest therefore that nutritional status and BMI should be evaluated when assessing the risk for falls in older age.
Copyright © 2018 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.
Language: en
LA - en SN - 1525-8610 UR - http://dx.doi.org/10.1016/j.jamda.2018.10.027 ID - ref1 ER -