TY  - JOUR
PY  - 2019//
TI  - Placental histology after minor trauma in pregnancy: a pilot study
JO  - Pediatric and developmental pathology
A1  - van der Knoop, B. J.
A1  - van der Voorn, J. P.
A1  - Nikkels, Pgj
A1  - Zonnenberg, I. A.
A1  - van Weissenbruch, M. M.
A1  - Vermeulen, R. J.
A1  - de Vries, Jip
SP  - 221
EP  - 228
VL  - 22
IS  - 3
N2  - OBJECTIVE Trauma in pregnancy may cause placental abruption. Consequences of moderate placental injury on neurodevelopment are unknown. The aim was to evaluate placental histology after maternal trauma. <br><br>METHODS A prospective study was conducted at 2 tertiary medical centers in the Netherlands. Placentas from women exposed to maternal trauma ≥ 20 weeks' gestational age were histologically examined. Neurological follow-up of the infants was performed at 1 year of age by means of Alberta Infant Motor Scale. Histological findings were compared to placentas from pregnancies without trauma. Principal Results Thirteen placentas were investigated in the trauma group. The control group consisted of 15 placentas. Placental pathology was seen more often in the trauma cases (11 of the 13) than in the controls (6 of the 15), P = .024. Neurological follow-up was normal. <br><br>CONCLUSIONS In this small population, majority of the placentas showed pathology after minor trauma in pregnancy without consequences for neurodevelopment at 1 year.<p />  <p>Language: en</p>
LA  - en
SN  - 1093-5266
UR  - http://dx.doi.org/10.1177/1093526618799292
ID  - ref1
ER  -