TY - JOUR PY - 2006// TI - Serotonin Transporter (5-HTTLPR) Genotype, Childhood Abuse, and Suicide Attempts in Adult Psychiatric Inpatients JO - Suicide and life-threatening behavior A1 - Gibb, Brandon E. A1 - McGeary, John E. A1 - Beevers, Christopher G. A1 - Miller, Ivan W. SP - 687 EP - 693 VL - 36 IS - 6 N2 - There is growing evidence that a functional polymorphism in the serotonin transporter gene (5-HTTLPR) moderates the impact of negative life events (e.g., childhood abuse) on the development of depression. However, it is unclear whether the gene x environment interaction predicts suicide attempts specifically. In addition, previous studies have not examined different forms of childhood abuse separately. In the current study, we found that 5-HTTLPR genotype moderated the link between childhood physical and sexual, but not emotional, abuse and adult psychiatric inpatients' histories of suicide attempts.

Language: en

LA - en SN - 0363-0234 UR - http://dx.doi.org/10.1521/suli.2006.36.6.687 ID - ref1 ER -