TY  - JOUR
PY  - 2019//
TI  - Medication, hospitalizations and mortality in 5 years after first-episode psychosis in a Swedish nation-wide cohort
JO  - Early intervention in psychiatry
A1  - Strålin, Pontus
A1  - Hetta, Jerker
SP  - 902
EP  - 907
VL  - 13
IS  - 4
N2  - AIM: To investigate medication, rehospitalizations and mortality after first-episode hospital-treated psychosis. <br><br>METHODS: A population-based nation-wide cohort (n = 2488) with a first hospitalization for psychosis at ages between 16 and 25 was identified. Cases were followed for up to 5 years after the first psychosis hospitalization with regard to mortality, hospitalizations and dispensations of antipsychotics and benzodiazepines. <br><br>RESULTS: The proportion of patients dispensing antipsychotics decreased from 80% year 1 after first discharge to 55% year 5. The proportion of patients having episodes of inpatient care also decreased year by year from 46% year 1 to 27% year 5. Of 863 cases with 5 years of observation time 41% had dispensations of antipsychotics every year; 21% had no dispensation of antipsychotics or hospitalization after the first year. The cumulative 5-year mortality was 3.9%. Cumulative suicide mortality was 2.4%. Incidence of suicide was highest in the first year. Male gender, benzodiazepines, recent hospital-discharge and self-harm were identified as risk factors for suicide. <br><br>CONCLUSIONS: The proportion of cases dispensing antipsychotics decreases year by year after first discharge. Mortality and rates of rehospitalization also decrease year by year from high levels the first year.<br><br>© 2018 John Wiley & Sons Australia, Ltd.<p />  <p>Language: en</p>
LA  - en
SN  - 1751-7885
UR  - http://dx.doi.org/10.1111/eip.12697
ID  - ref1
ER  -