TY - JOUR
PY - 2018//
TI - Risk of dementia after charcoal-burning suicide attempts: a nationwide cohort study in Taiwan
JO - Journal of investigative medicine
A1 - Chang, Shan-Yueh
A1 - Chien, Wu-Chien
A1 - Chung, Chi-Hsiang
A1 - Chang, Hsin-An
A1 - Kao, Yu-Chen
A1 - Yeh, Hui-Wen
A1 - Chou, Yu-Ching
A1 - Peng, Chung-Kan
A1 - Shen, Chih-Hao
A1 - Tzeng, Nian-Sheng
SP - 1070
EP - 1082
VL - 66
IS - 7
N2 - This study aimed to investigate the association between charcoal-burning suicide attempts and the risk of developing dementia. A nationwide, matched cohort, population-based study enrolled a total of 4103 patients with newly diagnosed charcoal-burning suicide attempts, between 2000 and 2010, which were selected from the National Health Insurance Research Database of Taiwan, along with 12,309 controls matched for sex and age. After adjusting for confounding factors, Fine and Gray's competing risk analysis was used to compare the risk of developing dementia during the 10-year follow-up period. Of the enrolled patients (n=16,412), dementia developed in 303 (1.85%), including 2.56% in the study group (105 in 4103) and 1.61% (198 in 12,309) in the control group. The Fine and Gray's survival analysis revealed that the patients with charcoal-burning suicide attempts were likely to develop dementia, with a crude HR of 5.170 (95% CI 4.022 to 6.644, p<0.001). After adjusting for age, sex, comorbidity, geographic area and urbanization level of residence, and monthly insured premium, the adjusted HR was 4.220 (95% CI 3.188 to 5.586, p<0.001). Suicide attempts were associated with an increased risk of degenerative dementia in this study. Patients with charcoal-burning suicide attempts had a fourfold risk of dementia than the control group.
© American Federation for Medical Research (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. Language: en
LA - en
SN - 1081-5589
UR - http://dx.doi.org/10.1136/jim-2018-000759
ID - ref1
ER -