TY  - JOUR
PY  - 2018//
TI  - Reduced dual-task gait speed is associated with visual Go/No-Go brain network activation in children and adolescents with concussion
JO  - Brain injury
A1  - Howell, David R.
A1  - Meehan, William P.
A1  - Barber Foss, Kim D.
A1  - Reches, Amit
A1  - Weiss, Michal
A1  - Myer, Gregory D.
SP  - 1129
EP  - 1134
VL  - 32
IS  - 9
N2  - OBJECTIVE: To investigate the association between dual-task gait performance and brain network activation (BNA) using an electroencephalography (EEG)-based Go/No-Go paradigm among children and adolescents with concussion. <br><br>METHODS: Participants with a concussion completed a visual Go/No-Go task with collection of electroencephalogram brain activity. Data were treated with BNA analysis, which involves an algorithmic approach to EEG-ERP activation quantification. Participants also completed a dual-task gait assessment. The relationship between dual-task gait speed and BNA was assessed using multiple linear regression models. <br><br>RESULTS: Participants (n = 20, 13.9 ± 2.3 years of age, 50% female) were tested at a mean of 7.0 ± 2.5 days post-concussion and were symptomatic at the time of testing (post-concussion symptom scale = 40.4 ± 21.9). Slower dual-task average gait speed (mean = 82.2 ± 21.0 cm/s) was significantly associated with lower relative time BNA scores (mean = 39.6 ± 25.8) during the No-Go task (β = 0.599, 95% CI = 0.214, 0.985, p = 0.005, R<sup>2</sup> = 0.405), while controlling for the effect of age and gender. <br><br>CONCLUSION: Among children and adolescents with a concussion, slower dual-task gait speed was independently associated with lower BNA relative time scores during a visual Go/No-Go task. The relationship between abnormal gait behaviour and brain activation deficits may be reflective of disruption to multiple functional abilities after concussion.<p />  <p>Language: en</p>
LA  - en
SN  - 0269-9052
UR  - http://dx.doi.org/10.1080/02699052.2018.1482424
ID  - ref1
ER  -