TY  - JOUR
PY  - 2018//
TI  - Electroencephalographic and cardiovascular markers of vulnerability within families of suicidal adolescents: a pilot study
JO  - Biological psychology
A1  - Kaufman, Erin A.
A1  - Crowell, Sheila E.
A1  - Coleman, James
A1  - Puzia, Megan E.
A1  - Gray, Douglas D.
A1  - Strayer, David L.
SP  - 46
EP  - 56
VL  - 136
IS  - 
N2  - Suicide, self-injury, and predisposing vulnerabilities aggregate in families. Those at greatest risk often show deficits in two biologically-mediated domains: behavioral control and emotion regulation. This pilot study explored electroencephalographic and cardiovascular indices of self-regulation among typical and suicidal adolescents (n = 30/group) and biological family members (mothers, fathers, and siblings). We measured event-related potentials during a flanker task designed to evoke impulsive responding and respiratory sinus arrhythmia (RSA) at rest and during social rejection. Multilevel models indicate control families' RSA was unaffected by social rejection (slope = 0.136, p = .097, d = 0.09), whereas clinical families demonstrated RSA withdrawal (slope = -0.191, p = .036, d = -0.13). Clinical families displayed weaker positive voltage (P<sub>e</sub>) deflections following behavioral errors relative to controls (coefficient = -2.723, p = .017, d = -0.45), indicating risk for compromised cognitive control. Thus, families with suicidal adolescents showed autonomic and central nervous system differences in biological markers associated with suicide risk.<br><br>Copyright © 2018 Elsevier B.V. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0301-0511
UR  - http://dx.doi.org/10.1016/j.biopsycho.2018.05.007
ID  - ref1
ER  -