TY  - JOUR
PY  - 2018//
TI  - Prophylactic use of steroids and antibiotics in acute hydrocarbon poisoning in children
JO  - Journal of pharmacy practice
A1  - Das, Saibal
A1  - Behera, Sapan Kumar
A1  - Xavier, Alphienes Stanley
A1  - Selvarajan, Sandhiya
SP  - 897190018771520
EP  - 897190018771520
VL  - ePub
IS  - ePub
N2  - Ingestion of hydrocarbons is a common cause of childhood poisoning in low and middle-income countries. Although mild ingestions are usually devoid of complications, the morbidity and mortality associated with such poisoning are primarily related to pulmonary aspiration. Subsequent complications, most importantly, secondary bacterial infections can worsen the clinical condition. Standard treatment protocol for acute accidental hydrocarbon poisoning does not advocate routine use of steroids or antibiotics. However, some studies have demonstrated beneficial effects of prophylactic steroid and antibiotic to prevent chemical pneumonitis. In this article, we have summarized the findings of the clinical studies from literature, which have evaluated the advantages of early administration of steroids and antibiotics to prevent chemical pneumonitis in acute hydrocarbon poisoning in children. From these studies, we have found that there is no convincing evidence for initiating steroid and antibiotic to improve outcome in these children.<p />  <p>Language: en</p>
LA  - en
SN  - 0897-1900
UR  - http://dx.doi.org/10.1177/0897190018771520
ID  - ref1
ER  -