TY - JOUR
PY - 2018//
TI - Apathy following traumatic brain injury: a review
JO - Neuropsychologia
A1 - Worthington, Andrew
A1 - Wood, Rodger Ll
SP - 40
EP - 47
VL - 118
IS - Pt B
N2 - Apathy is a common problem after traumatic brain injury (TBI) and can have a major impact on cognitive function, psychosocial outcome and engagement in rehabilitation. For scientists and clinicians it remains one of the least understood aspects of brain-behaviour relationships encompassing disturbances of cognition, motivation, emotion and action, and is variously an indication of organic brain disease or psychiatric disorder. Apathy can be both sign and symptom and has been proposed as a diagnosis in its own right as well as a secondary feature of other conditions. This review considers previous approaches to apathy in terms of relevant psychological constructs and those neural counterparts most likely to be implicated after TBI. Neurobehavioural disorders of apathy are characterised chiefly by dysfunction of executive control of goal-oriented behaviour or the neural substrates of reward-based and emotional learning. We argue that it is possible to distinguish a primary disorder of apathy as an organic neurobehavioural state from secondary presentations due to an impoverished environment or psychological disturbance which has implications for treatment.
Copyright © 2018. Published by Elsevier Ltd.
Language: en
LA - en SN - 0028-3932 UR - http://dx.doi.org/10.1016/j.neuropsychologia.2018.04.012 ID - ref1 ER -