TY  - JOUR
PY  - 2018//
TI  - The increase in copeptin levels in mild head trauma does not predict the severity and the outcome of brain damage
JO  - Biomarkers in medicine
A1  - Casello, Luigi M.
A1  - Salmi, Livia
A1  - Zanotti, Isabella
A1  - Gardino, Clara A.
A1  - Baldrighi, Marco
A1  - Settanni, Fabio
A1  - Avanzi, Gian C.
SP  - 555
EP  - 563
VL  - 12
IS  - 6
N2  - AIM: To investigate the copeptin prognostic role in mild head trauma. <br><br>METHODS: We enrolled 105 adult patients who entered the emergency room because of recent mild head trauma; we evaluated: clinical picture, imaging and laboratory data (including copeptin). <br><br>RESULTS: Copeptin resulted higher in mild head trauma patients compared with controls: 29.89 pmol/l versus 7.05 pmol/l; (p = 0.0008). Copeptin failed in identifying patients with or without brain lesions detected by CT scan, and patients with or without adverse events during the 30 days follow-up. <br><br>CONCLUSION: We confirmed that mild head trauma patients have a significantly higher copeptin plasma levels compared with controls. Nevertheless, we did not observe a significant role for copeptin in traumatic brain injury patients regarding brain damage and outcome.<p />  <p>Language: en</p>
LA  - en
SN  - 1752-0363
UR  - http://dx.doi.org/10.2217/bmm-2018-0041
ID  - ref1
ER  -