TY  - JOUR
PY  - 2017//
TI  - Cholinesterase activity assays and their use in the diagnosis of various pathological states including poisoning by neurotoxic agents
JO  - Czech and Slovak Pharmacy
A1  - Pohanka, Miroslav
SP  - 147
EP  - 153
VL  - 66
IS  - 4
N2  - Cholinesterases are enzymes important for some nerve transmissions where the enzyme acetylcholinesterase plays a crucial role. The second enzyme, butyrylcholinesterase, is not necessary for the neurotransmission but it is involved in some detoxification reactions. A survey of literature, a discussion of diagnostic importance and the methods for an activity assay are presented in this review article. Liver failures, exposure to neurotoxic compounds, genetic dispositions are outlined here. In the field of assays, spectrophotometric, colorimetric and electrochemical tests are discussed.    Key words: acetylcholinesterase butyrylcholinesterase poisoning liver function test pesticide nerve agent Alzheimer disease pathological state.<p />  <p>Language: cs</p>
LA  - cs
SN  - 1210-7816
UR  - http://dx.doi.org/
ID  - ref1
ER  -