TY - JOUR PY - 2018// TI - Longitudinal determinants of depression among World Trade Center Health Registry enrollees, 14-15 years after the 9/11 attacks JO - Journal of affective disorders A1 - Jacobson, Melanie H. A1 - Norman, Christina A1 - Nguyen, Angela A1 - Brackbill, Robert M. SP - 483 EP - 490 VL - 229 IS - N2 - BACKGROUND: Exposure to the September 11, 2001 (9/11) terrorist attacks has been found to be associated with posttraumatic stress disorder (PTSD) and comorbid PTSD and depression up to 10-11 years post-disaster. However, little is known about the longitudinal predictors of mental health conditions over time.

METHODS: We examined longitudinal determinants of depression within strata of PTSD among 21,258 enrollees of the World Trade Center Health Registry who completed four questionnaires over 14 years of follow-up (Wave 1 in 2003-04; Wave 2 in 2005-06; Wave 3 in 2011-12; and Wave 4 in 2015-16). PTSD status was measured using the PTSD checklist on all four waves and defined as a score of ≥ 44; depression was assessed using the 8-item Patient Health Questionnaire at Waves 3 and 4 and defined as a score of ≥ 10.

RESULTS: Across Waves 3 and 4, 18.6% experienced depression, and it was more common among those who ever had PTSD (56.1%) compared with those who had not (5.6%). Across PTSD strata, predictors of depression included low income, unemployment, low social integration and support, post-9/11 traumatic life events, and chronic physical illness. These factors also decreased the likelihood of recovering from depression. LIMITATIONS: Depression symptoms were not measured at Waves 1 and 2; data was self-reported.

CONCLUSIONS: These findings highlight the substantial burden of depression in a trauma-exposed population 14-15 years post-disaster, especially among those with PTSD. Similar life stressors predicted the course of depression among those with and without PTSD which may inform public health and clinical interventions.

Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

Language: en

LA - en SN - 0165-0327 UR - http://dx.doi.org/10.1016/j.jad.2017.12.105 ID - ref1 ER -