TY  - JOUR
PY  - 2017//
TI  - Evaluating clinical risk factors for suicide attempts in patients with epilepsy
JO  - Journal of affective disorders
A1  - Harnod, Tomor
A1  - Lin, Cheng-Li
A1  - Kao, Chia-Hung
SP  - 79
EP  - 84
VL  - 229
IS  - 
N2  - OBJECTIVE: We would like to exam whether epilepsy patients in Taiwan have a high risk of attempted and completed suicide. <br><br>METHODS: In this study, we used a subset of the National Health Insurance Research Database (NHIRD) of Taiwan. Inpatients (≥ 18 years) who received a new diagnosis of epilepsy between 2000 and 2011 were enrolled in the epilepsy cohort. The epilepsy and comparison cohorts included 68,543 patients and 2-fold controls respectively. We calculated the adjusted hazard ratio (aHR) for suicide attempts after adjustment for age, sex, monthly income, the urbanization level, occupation, and comorbidity. <br><br>RESULTS: The epilepsy cohort had a 2.06-fold risk of suicide attempts (95% CI = 1.65-2.56) compared with the control cohort. The suicide attempt risk did not significantly differ between men and women and between patients with and without psychiatric comorbidity. The mortality risk after a suicide attempt was higher in the epilepsy cohort than in the comparison cohort (aHR = 1.66, 95% CI = 1.02-2.69). <br><br>CONCLUSION: Epilepsy is an independent and predisposing factor for suicide attempt. These results provide important information for clinicians and governments to prevent suicide in epilepsy patients in Asian countries.<br><br>Copyright © 2017 Elsevier B.V. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0165-0327
UR  - http://dx.doi.org/10.1016/j.jad.2017.12.048
ID  - ref1
ER  -