TY - JOUR PY - 2018// TI - Reduced dorsolateral prefrontal cortex activation during affective Go/NoGo in violent schizophrenia patients: an fMRI study JO - Schizophrenia Research A1 - Tikàsz, Andràs A1 - Potvin, Stéphane A1 - Richard-Devantoy, Stéphane A1 - Lipp, Olivier A1 - Hodgins, Sheilagh A1 - Lalonde, Pierre A1 - Lungu, Ovidiu A1 - Dumais, Alexandre SP - 249 EP - 252 VL - 197 IS - N2 - We investigated the influence of anger processing on cognitive control in male schizophrenia patients presenting violent behaviors. We recruited 23 patients without and 24 patients with (SCZ+V) a history of violent behaviors, as well as 22 healthy non-violent men. Participants were administered an affective (angry-neutral faces) Go/NoGo task while undergoing functional magnetic resonance imaging. We found a reduced activation in the dorsolateral prefrontal cortex in SCZ+V patients specifically when inhibiting a response while viewing angry faces. These results show an inability of SCZ+V to recruit a core region of the (inhibitory) cognitive control network in the context of anger.

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Language: en

LA - en SN - 0920-9964 UR - http://dx.doi.org/10.1016/j.schres.2017.11.011 ID - ref1 ER -