TY - JOUR
PY - 2018//
TI - Reduced dorsolateral prefrontal cortex activation during affective Go/NoGo in violent schizophrenia patients: an fMRI study
JO - Schizophrenia Research
A1 - Tikàsz, Andràs
A1 - Potvin, Stéphane
A1 - Richard-Devantoy, Stéphane
A1 - Lipp, Olivier
A1 - Hodgins, Sheilagh
A1 - Lalonde, Pierre
A1 - Lungu, Ovidiu
A1 - Dumais, Alexandre
SP - 249
EP - 252
VL - 197
IS -
N2 - We investigated the influence of anger processing on cognitive control in male schizophrenia patients presenting violent behaviors. We recruited 23 patients without and 24 patients with (SCZ+V) a history of violent behaviors, as well as 22 healthy non-violent men. Participants were administered an affective (angry-neutral faces) Go/NoGo task while undergoing functional magnetic resonance imaging. We found a reduced activation in the dorsolateral prefrontal cortex in SCZ+V patients specifically when inhibiting a response while viewing angry faces. These results show an inability of SCZ+V to recruit a core region of the (inhibitory) cognitive control network in the context of anger.
Copyright © 2017 Elsevier B.V. All rights reserved.
Language: en
LA - en SN - 0920-9964 UR - http://dx.doi.org/10.1016/j.schres.2017.11.011 ID - ref1 ER -