TY  - JOUR
PY  - 2017//
TI  - Death by self-mutilation after oral cannabis consumption
JO  - Legal medicine (Elsevier)
A1  - Delteil, Clemence
A1  - Sastre, Caroline
A1  - Piercecchi, Marie-Dominique
A1  - Faget-Agius, Catherine
A1  - Deveaux, Marc
A1  - Kintz, Pascal
A1  - Devooght, Marc-Antoine
A1  - Leonetti, George
A1  - Bartoli, Christophe
A1  - Pélissier-Alicot, Anne-Laure
SP  - 5
EP  - 9
VL  - 30
IS  - 
N2  - Major self-mutilation (amputation, castration, self-inflicted eye injuries) is frequently associated with psychiatric disorders and/or substance abuse. A 35-year-old man presented with behavioral disturbances of sudden onset after oral cannabis consumption and major self-mutilation (attempted amputation of the right arm, self-enucleation of both eyes and impalement) which resulted in death. During the enquiry, four fragments of a substance resembling cannabis resin were seized at the victim's home. Autopsy confirmed that death was related to hemorrhage following the mutilations. Toxicological findings showed cannabinoids in femoral blood (tetrahydrocannabinol (THC) 13.5 ng/mL, 11-hydroxy-tetrahydrocannabinol (11-OH-THC) 4.1 ng/mL, 11-nor-9-carboxy-THC (THC-COOH) 14.7 ng/mL, cannabidiol (CBD) 1.3 ng/mL, cannabinol (CBN) 0.7 ng/mL). Cannabinoid concentrations in hair (1.5 cm brown hair strand/1 segment) were consistent with concentrations measured in chronic users (THC 137 pg/mg, 11-OH-THC 1 pg/mg, CBD 9 pg/mg, CBN 94 pg/mg). Analysis of the fragments seized confirmed that this was cannabis resin with high levels of THC (31-35%). We discuss the implications of oral consumption of cannabis with a very high THC content.<br><br>Copyright © 2017 Elsevier B.V. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 1344-6223
UR  - http://dx.doi.org/10.1016/j.legalmed.2017.10.010
ID  - ref1
ER  -