TY  - JOUR
PY  - 2017//
TI  - Suicide attempts in juvenile bipolar versus major depressive disorders: systematic review and meta-analysis
JO  - Journal of the American Academy of Child and Adolescent Psychiatry
A1  - De Crescenzo, Franco
A1  - Serra, Giulia
A1  - Maisto, Francesco
A1  - Uchida, Mai
A1  - Woodworth, Hilary
A1  - Casini, Maria Pia
A1  - Baldessarini, Ross J.
A1  - Vicari, Stefano
SP  - 825
EP  - 831.e3
VL  - 56
IS  - 10
N2  - OBJECTIVE: Suicide attempts are prevalent in association with major mood disorders, and risk is greater with bipolar disorder (BD) than major depressive disorder (MDD) in adults. There may be similar relationships in juvenile mood disorders, but the evidence has not been compiled systematically and quantitatively. <br><br>METHOD: We searched for reports of studies comparing rates of suicide attempts in children or adolescents diagnosed with BD or MDD, and applied random-effects meta-analysis. <br><br>RESULTS: In 6 reports from 1995 to 2017, with 2,303 participants diagnosed with mood disorder from the United States and South Korea, aged 3 to 18 years, rates of suicide attempts differed significantly by diagnosis: BD (31.5%) > MDD (20.5%) > hypomania or mania-only (8.49%). Risk of suicide attempts differed (BD > MDD) highly significantly by meta-analysis (odds ratio [OR] = 1.71, CI = 1.33-2.20, p <.0001), and was very similar if a study with attempts and suicidal ideation was excluded (OR = 1.64, CI = 1.26-2.15, p <.0001). <br><br>CONCLUSION: Risk of suicide attempts in juvenile mood disorder patients ranked: BD > MDD > hypomania or mania-only > juvenile general population.<br><br>Copyright © 2017 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0890-8567
UR  - http://dx.doi.org/10.1016/j.jaac.2017.07.783
ID  - ref1
ER  -