TY  - JOUR
PY  - 2018//
TI  - The minimal clinically important difference for the Rasch neuropsychiatric inventory irritability and aggression scale for traumatic brain injury
JO  - Archives of physical medicine and rehabilitation
A1  - Malec, James F.
A1  - Hammond, Flora M.
SP  - 603
EP  - 606.e1
VL  - 99
IS  - 3
N2  - OBJECTIVE: To determine the Minimal Clinically Important Difference (MCID) for a Rasch measure derived from the Irritability/Lability and Agitation/Aggression subscales of the Neuropsychiatric Inventory (NPI-TBI-IA). <br><br>DESIGN: Distribution-based statistical methods were applied to retrospective data to determine candidates for the MCID. These candidates were evaluated by anchoring the NPI-TBI-IA to Global Impression of Change (GIC) ratings by participants, significant others, and a supervising physician. MAIN OUTCOME MEASURE: NPI-TBI-IA. SETTING: Postacute rehabilitation outpatient clinic. PARTICIPANTS: 274 cases with observer ratings; 232 cases with self-ratings by participants with moderate-severe TBI at least 6 months post-injury. <br><br>RESULTS: For observer ratings on the NPI-TBI-IA, anchored comparisons found an improvement of ½ SD was associated with at least minimal general improvement on GIC by a significant majority (69-80%); ½ SD improvement on participant NPI-TBI-IA self-ratings was also associated with at least minimal improvement on the GIC by a substantial majority (77-83%). The percent indicating significant global improvement did not increase markedly on most ratings at higher levels of improvement on the NPI-TBI-IA. <br><br>CONCLUSIONS: A ½ SD improvement on the NPI-TBI-IA indicates the MCID for both observer and participant ratings on this measure.<br><br>Copyright © 2017. Published by Elsevier Inc.<p />  <p>Language: en</p>
LA  - en
SN  - 0003-9993
UR  - http://dx.doi.org/10.1016/j.apmr.2017.06.038
ID  - ref1
ER  -