TY  - JOUR
PY  - 2017//
TI  - Central diabetes insipidus and hyperglycemic hyperosmolar state following accidental carbon monoxide poisoning
JO  - Curēus
A1  - Ul Abideen, Zain
A1  - Mahmud, Syed Nayer
A1  - Rasheed, Amna
A1  - Farooq Qasim, Yusaf
A1  - Ali, Furqan
SP  - e1305
EP  - e1305
VL  - 9
IS  - 6
N2  - Carbon monoxide poisoning is common and carries significant morbidity and mortality. The nervous system, particularly the brain, is frequently affected by it, owing to its high metabolic activity and oxygen requirements. Carbon monoxide damages the nervous system by both hypoxic and inflammatory mechanisms. Central diabetes insipidus is an extremely rare complication of carbon monoxide poisoning. Herein, we report the case of a young lady, who developed this complication and severe hypernatremia after accidental carbon monoxide poisoning. She also developed a hyperglycemic hyperosmolar state during the treatment for hypernatremia. To the best of our knowledge, both these entities have not been reported together in association with carbon monoxide poisoning. The purpose of this article is to emphasize the anticipation and early recognition of central diabetes insipidus in carbon monoxide poisoning. This can prevent severe hypernatremia and complications associated with its presence and treatment.<p />  <p>Language: en</p>
LA  - en
SN  - 2168-8184
UR  - http://dx.doi.org/10.7759/cureus.1305
ID  - ref1
ER  -