TY  - JOUR
PY  - 2017//
TI  - The maximum tolerated dose of walking for community-dwelling people recovering from hip fracture: a dose-response trial
JO  - Archives of physical medicine and rehabilitation
A1  - Peiris, Casey
A1  - Shields, Nora
A1  - Kingsley, Michael
A1  - Yeung, Jack
A1  - Hau, Raphael
A1  - Taylor, Nicholas
SP  - 2533
EP  - 2539
VL  - 98
IS  - 12
N2  - OBJECTIVE: To determine how much moderate-intensity physical activity, in the form of walking, could be prescribed for people living in the community after hip fracture in terms of safety, tolerability and feasibility. <br><br>DESIGN: Phase I dose-response design. SETTING: Participants were recruited from two public community rehabilitation centres in Melbourne, Australia. PARTICIPANTS: Community-dwelling adults (n=21, 16 women, mean age ± SD, 75 ± 9 years) who were cognitively alert, attending community rehabilitation after a hip fracture (mean ± SD days post fracture, 110 ± 47 days), able to walk with or without a gait aid and for whom it was safe to participate in physical activity. INTERVENTION: Individually supervised doses of moderate intensity walking completed in one week in addition to their usual levels of physical activity. Three participants were required to complete a dose of walking prior to dose escalation for the next cohort of three participants. Dose escalation ceased when more than one participant in a cohort had an adverse event or was unable to tolerate the dose or if the maximum dose of 150 minutes per week was achieved. MAIN OUTCOME MEASURES: Maximum tolerated dose of walking per week (minutes), adverse events, mobility and walking confidence. <br><br>RESULTS: The maximum tolerated dose of walking for adults after hip fracture before significant discomfort was experienced (e.g. breathlessness, pain, fatigue) by any participant was 100 minutes per week. No adverse events occurred but participants began to be unable to tolerate higher doses beyond 100 minutes per week. <br><br>CONCLUSIONS: This provides preliminary evidence that community-dwelling older adults recovering from hip fracture can complete a sufficient amount of moderate intensity physical activity to maintain and improve their health.<br><br>Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0003-9993
UR  - http://dx.doi.org/10.1016/j.apmr.2017.03.027
ID  - ref1
ER  -