TY  - JOUR
PY  - 2017//
TI  - Increased postural sway in persons with multiple sclerosis during short-term exposure to warm ambient temperatures
JO  - Gait and posture
A1  - Poh, Paula Y. S.
A1  - Adams, Amy N.
A1  - Huang, Mu
A1  - Allen, Dustin R.
A1  - Davis, Scott L.
A1  - Tseng, Anna S.
A1  - Crandall, Craig G.
SP  - 230
EP  - 235
VL  - 53
IS  - 
N2  - BACKGROUND: Multiple sclerosis (MS) is a neurological disease marked by demyelination and axonal loss. Individuals with MS experience increases in clinical signs and symptoms during heat exposure. <br><br>OBJECTIVE: To test the hypothesis that moderate heat exposure adversely affects postural sway in individuals with MS. <br><br>METHODS: Ten individuals with relapsing-remitting MS (50±8y) and nine controls (47±10y) were examined under a Thermal and a Time Control trial. Following a 30min thermoneutral baseline (25°C, 30% relative humidity (RH)), stand tests randomized with eyes open and closed, were performed. For Thermal, subjects were first exposed to 60min of heating (40°C, 30%RH) followed by 60min of cooling (20°C, 30%RH). For Time Control, subjects remained in a thermoneutral environment throughout. Stand tests were repeated at consistent times in both trials. <br><br>RESULTS: No difference in skin and core temperatures between groups were observed for any trial (P>0.05). During heating, postural sway was higher in MS relative to control subjects (eyes open, P=0.03; eyes closed, P=0.011). No differences in postural sway, regardless of eye status, were observed during the Time Control trial for either group (P>0.05). <br><br>CONCLUSION: These data demonstrate that exposure to a moderate heating environment increases postural sway in patients with MS.<br><br>Copyright © 2017 Elsevier B.V. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0966-6362
UR  - http://dx.doi.org/10.1016/j.gaitpost.2017.01.025
ID  - ref1
ER  -