TY - JOUR
PY - 2016//
TI - Differential associations of affective temperaments and diagnosis of major affective disorders with suicidal behavior
JO - Journal of affective disorders
A1 - Baldessarini, Ross J.
A1 - Innamorati, Marco
A1 - Erbuto, Denise
A1 - Serafini, Gianluca
A1 - Fiorillo, Andrea
A1 - Amore, Mario
A1 - Girardi, Paolo
A1 - Pompili, Maurizio
SP - 19
EP - 21
VL - 210
IS -
N2 - BACKGROUND: Affective temperaments are associated with suicidal risk, but their predictive value relative to diagnosis of major affective disorder is uncertain.
METHODS: We compared diagnoses, affective-temperament ratings (TEMPS-A), and other potential risk factors in 956 psychiatric inpatients, using bivariate analyses and multivariable logistic regression modeling for associations with suicidal status.
RESULTS: Lifetime suicide-attempt rates were high (43.9% overall), ranking by diagnosis: bipolar-II (58.4%), major depressive (50.0%), bipolar-I (44.6%), other (38.0%), and psychotic (33.9%) disorders. TEMPS-A scores for depressive (dep), cyclothymic (cyc), irritable (irr), and anxious (anx) temperaments and their sum were strongly associated with suicidal risk; hyperthymic (hyp) temperament scores were inversely associated; and a composite measure (dep+cyc+irr+anx - hyp), even more strongly associated. The composite score was highly, independently associated with suicidal behavior (p<0.0001), as was female sex (p=0.0002), but older age and diagnosis of major affective disorder, much less (both p=0.02).
CONCLUSIONS: Measures of affective temperament-types were independently and more strongly associated with lifetime suicide attempt than was diagnosis of a major affective disorder. However, in this hospitalized cohort, suicide rates were high across diagnoses, possibly limiting the predictive value of diagnosis.
Copyright © 2016 Elsevier B.V. All rights reserved. Language: en
LA - en
SN - 0165-0327
UR - http://dx.doi.org/10.1016/j.jad.2016.12.003
ID - ref1
ER -