TY  - JOUR
PY  - 2016//
TI  - Pathophysiology, research challenges, and clinical management of smoke inhalation injury
JO  - Lancet
A1  - Enkhbaatar, Perenlei
A1  - Pruitt, Basil A.
A1  - Suman, Oscar
A1  - Mlcak, Ronald
A1  - Wolf, Steven E.
A1  - Sakurai, Hiroyuki
A1  - Herndon, David N.
SP  - 1437
EP  - 1446
VL  - 388
IS  - 10052
N2  - Smoke inhalation injury is a serious medical problem that increases morbidity and mortality after severe burns. However, relatively little attention has been paid to this devastating condition, and the bulk of research is limited to preclinical basic science studies. Moreover, no worldwide consensus criteria exist for its diagnosis, severity grading, and prognosis. Therapeutic approaches are highly variable depending on the country and burn centre or hospital. In this Series paper, we discuss understanding of the pathophysiology of smoke inhalation injury, the best evidence-based treatments, and challenges and future directions in diagnostics and management.<br><br>Copyright © 2016 Elsevier Ltd. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0140-6736
UR  - http://dx.doi.org/10.1016/S0140-6736(16)31458-1
ID  - ref1
ER  -