TY  - JOUR
PY  - 2016//
TI  - Development of a library search-based screening system for 3,4-methylenedioxymethamphetamine in ecstasy tablets using a portable near-infrared spectrometer
JO  - Journal of forensic sciences
A1  - Tsujikawa, Kenji
A1  - Yamamuro, Tadashi
A1  - Kuwayama, Kenji
A1  - Kanamori, Tatsuyuki
A1  - Iwata, Yuko T.
A1  - Miyamoto, Kazuna
A1  - Kasuya, Fumiyo
A1  - Inoue, Hiroyuki
SP  - 1208
EP  - 1214
VL  - 61
IS  - 5
N2  - This is the first report on development of a library search-based screening system for 3,4-methylenedioxymethamphetamine (MDMA) in ecstasy tablets using a portable near-infrared (NIR) spectrometer. The spectrum library consisted of spectra originating from standard substances as well as mixtures of MDMA hydrochloride (MDMA-HCl) and diluents. The raw NIR spectra were mathematically pretreated, and then, a library search was performed using correlation coefficient. To enhance the discrimination ability, the wavelength used for the library search was limited. Mixtures of MDMA-HCl and diluents were used to decide criteria to judge MDMA-positive or MDMA-negative. Confiscated MDMA tablets and medicinal tablets were used for performance check of the criteria. Twenty-two of 27 MDMA tablets were truly judged as MDMA-positive. Five false-negative results may be caused by compounds not included in the library. No false-positive results were obtained for medicinal tablets. This system will be a useful tool for on-site screening of MDMA tablets.<br><br>© 2016 American Academy of Forensic Sciences.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-1198
UR  - http://dx.doi.org/10.1111/1556-4029.13122
ID  - ref1
ER  -