TY  - JOUR
PY  - 2016//
TI  - The forensic diagnostics and interpretation of ethyl glucuronide concentrations (EtG) in serum, urine and hair samples
JO  - Zeitschrift für Verkehrssicherheit ZVS
A1  - Thieme, D.
A1  - Sachs, H.
A1  - Graw, M. H.
SP  - 20
EP  - 24
VL  - 62
IS  - 1
N2  - The forensic diagnostics and interpretation of ethanol consumption or abuse comprises the whole range of relevant blood ethanol concentrations and deals with abstinence control, ethanol-related impairment as well as addiction. Ethanol concentrations in blood proved to be particularly useful for any evaluation of acute biological effects. In addition, its biological inactive metabolite ethyl glucuronide (EtG) became an important marker for long-term interpretation of ethanol consumption due to its delayed elimination. By establishing robust threshold values of EtG in urine and hair samples, a semi-quantitative differentiation of ethanol abstinence became available. Moreover, excessive ethanol consumption can be identified by high hair concentrations due to the long-term accumulation of EtG. The evaluation of moderate concentrations - e. g. EtG in serum samples - requires much more complex considerations compared to these robust thresholds in cases of very low (negative) and extremely high levels. Application of kinetic models may permit an improved evaluation of declared ethanol consumptions, in particular in cases of post-offence drinking defense.<p />  <p>Language: de</p>
LA  - de
SN  - 0044-3654
UR  - http://dx.doi.org/
ID  - ref1
ER  -