TY  - JOUR
PY  - 2006//
TI  - Depression and Pesticide Exposures in Female Spouses of Licensed Pesticide Applicators in the Agricultural Health Study Cohort
JO  - Journal of Occupational and Environmental Medicine
A1  - Beseler, Cheryl
A1  - Stallones, Lorann
A1  - Hoppin, Jane A.
A1  - Alavanja, Michael C. R.
A1  - Blair, Aaron
A1  - Keefe, Thomas
A1  - Kamel, Freya
SP  - 1005
EP  - 1013
VL  - 48
IS  - 10
N2  - OBJECTIVE:: This nested case-control study evaluated the association between depression and pesticide exposure among women. METHODS:: The study population included 29,074 female spouses of private pesticide applicators enrolled in the Agricultural Health Study between 1993 and 1997. Cases were women who had physician-diagnosed depression requiring medication. Lifetime pesticide use was categorized as never mixed/applied pesticides, low exposure (up to 225 days), high exposure (>225 days), and a history of diagnosed pesticide poisoning. RESULTS:: After adjustment for state, age, race, off-farm work, alcohol, cigarette smoking, physician visits, and solvent exposure, depression was significantly associated with a history of pesticide poisoning (odds ratio [OR] = 3.26; 95% confidence interval [CI] = 1.72-6.19) but not low (OR = 1.09; CI = 0.91-1.31) or high (OR = 1.09; 95% CI = 0.91-1.31) cumulative pesticide exposure. CONCLUSION:: Pesticide poisoning may contribute to risk of depression.<p />  <p>Language: en</p>
LA  - en
SN  - 1076-2752
UR  - http://dx.doi.org/10.1097/01.jom.0000235938.70212.dd
ID  - ref1
ER  -