TY - JOUR PY - 2016// TI - Predictors of continued use of extended-released naltrexone (XR-NTX) for opioid-dependence: an analysis of heroin and non-heroin opioid users in Los Angeles County JO - Journal of substance abuse treatment A1 - Cousins, Sarah J. A1 - Radfar, Seyed Ramin A1 - Crèvecoeur-MacPhail, Desirée A1 - Ang, Alfonso A1 - Darfler, Kendall A1 - Rawson, Richard A. SP - 66 EP - 71 VL - 63 IS - N2 - Extended-release naltrexone (XR-NTX) is associated with an increased number of opioid-free days, improved adherence rates in substance use disorder treatment programs, and reduced cravings and drug-seeking behaviors. There is little evidence on the predictive associations between baseline characteristics of opioid-dependent patients and XR-NTX utilization. Some studies have demonstrated better pharmacotherapy adherence and/or retention rates among non-heroin opioid users compared to heroin users. This study examines predictive associations between characteristics of patients and XR-NTX utilization, as well as participants' urge to use opiates. Our findings suggest that XR-NTX may contribute to decreases in urges to use among both heroin and non-heroin opioid users. Non-heroin opioid users and heroin users were retained in XR-NTX treatment for comparable periods of time. However, those who identified as homeless, injected opioids (regardless of opioid-type), or were diagnosed with a mental illness were less likely to be retained in treatment with XR-NTX.

Language: en

LA - en SN - 0740-5472 UR - http://dx.doi.org/10.1016/j.jsat.2015.12.004 ID - ref1 ER -