TY - JOUR PY - 2015// TI - Myocardial injury without electrocardiographic changes after a suicide attempt by an overdose of glimepiride and zolpidem: a case report and literature review JO - Internal medicine A1 - Chou, Shengpu A1 - Ayabe, Seiji A1 - Sekine, Nobuo SP - 2727 EP - 2733 VL - 54 IS - 21 N2 - A 40-year-old diabetic man was admitted to our hospital for poor glycemic control. During hospitalization, he took 42 mg glimepiride and 50 mg zolpidem as a suicide attempt. The following day, the creatine kinase-MB fraction and troponin I levels were elevated to 112 IU/L and 8.77 ng/mL, respectively, without any electrocardiographic abnormalities. The patient recovered completely without any complications. Four weeks later, coronary computed tomography angiography and myocardial perfusion scintigraphy revealed moderate one-vessel coronary disease without the evidence of myocardial ischemia or old infarction. Cardiac-specific markers must be considered in sulfonylurea-induced hypoglycemic patients, particularly when the patient is unconscious and does not exhibit any clinical manifestations.

Language: en

LA - en SN - 0918-2918 UR - http://dx.doi.org/10.2169/internalmedicine.54.4748 ID - ref1 ER -