TY  - JOUR
PY  - 2015//
TI  - The effects of dextromethorphan on driving performance and the standardized field sobriety test
JO  - Journal of forensic sciences
A1  - Perry, Paul J.
A1  - Fredriksen, Kristian
A1  - Chew, Stephanie
A1  - Ip, Eric J.
A1  - Lopes, Ingrid
A1  - Doroudgar, Shadi
A1  - Thomas, Kelan
SP  - 1258
EP  - 1262
VL  - 60
IS  - 5
N2  - Dextromethorphan (DXM) is abused most commonly among adolescents as a recreational drug to generate a dissociative experience. The objective of the study was to assess driving with and without DXM ingestion. The effects of one-time maximum daily doses of DXM 120 mg versus a guaifenesin 400 mg dose were compared among 40 healthy subjects using a crossover design. Subjects' ability to drive was assessed by their performance in a driving simulator (STISIM(®) Drive driving simulator software) and by conducting a standardized field sobriety test (SFST) administered 1-h postdrug administration. The one-time dose of DXM 120 mg did not demonstrate driving impairment on the STISIM(®) Drive driving simulator or increase SFST failures compared to guaifenesin 400 mg. Doses greater than the currently recommended maximum daily dose of 120 mg are necessary to perturb driving behavior.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-1198
UR  - http://dx.doi.org/10.1111/1556-4029.12833
ID  - ref1
ER  -