TY  - JOUR
PY  - 2015//
TI  - Systems genetics of behavior: a prelude
JO  - Current opinion in behavioral sciences
A1  - Mulligan, Megan K.
A1  - Williams, Robert W.
SP  - 108
EP  - 115
VL  - 2
IS  - 
N2  - Behaviors are among the most complex phenotypes -- the end product of intertwined networks of genetic, molecular, cellular, physiological, environmental, and social factors. While reductionist methods that test contributions of single genes are crucial to define components of behavior, there are now complementary integrative methods that can model and predict behavior in a more global context. Systems genetics is a new field that exploits massive multiscalar data to study patterns of covariation in complex biological systems. As applied to behavioral genetics, this field looks inside the black box to understand hierarchies of molecular and cellular traits and connections that link gene variants and environment to behavior. Here we explore recent progress and challenges in this new field.<p />
LA  - en
SN  - 2352-1546
UR  - http://dx.doi.org/10.1016/j.cobeha.2015.01.014
ID  - ref1
ER  -