TY  - JOUR
PY  - 1995//
TI  - Evidence for dorsolateral and orbital prefrontal cortical involvement in the expression of aggressive behavior
JO  - Aggressive behavior
A1  - Giancola, Peter R.
SP  - 431
EP  - 450
VL  - 21
IS  - 6
N2  - Numerous studies have implicated the role of the prefrontal cortex in the expression of aggressive behavior, However, the nature of this relationship remains poorly understood. As such, the purpose of this article is to review both the animal and human literature pertaining to prefrontal cortical functioning and aggression in an attempt to help clarify this relationship. Particular attention is paid to differentiating the functions of the dorsolateral and the orbital regions of the prefrontal cortex in the expression of aggression. Evidence was garnered from four different types of studies: 1) those examining aggressive behavior in animals following ablations to the prefrontal cortex; 2) those examining aggressive behavior in humans following surgical and accidental lesions to the prefrontal cortex; 3) those examining prefrontal cortical functioning in individuals with psychiatric disorders characterized by aggression; and 4) those relating prefrontal cortical functioning to human aggressive behavior in laboratory situations. The general conclusion of this article is that the dorsolateral region of the prefrontal cortex is more likely to be involved in the expression of physical aggression whereas the orbital region is more likely to be involved in the expression of what is termed herein 'disinhibited-nonaggressive' behavior.<p />
LA  - en
SN  - 0096-140X
UR  - http://dx.doi.org/
ID  - ref1
ER  -