TY - JOUR PY - 2015// TI - An acute acetyl fentanyl fatality: a case report with postmortem concentrations JO - Journal of analytical toxicology A1 - McIntyre, Iain M. A1 - Trochta, Amber A1 - Gary, Ray D. A1 - Malamatos, Mark A1 - Lucas, Jonathan R. SP - 490 EP - 494 VL - 39 IS - 6 N2 - In this case report, we present an evaluation of the distribution of postmortem concentrations of acetyl fentanyl in a fatality attributed to the drug. A young man who had a history of heroin abuse was found deceased at his parents' home. Toxicology testing, which initially screened positive for fentanyl by ELISA, subsequently confirmed acetyl fentanyl by gas chromatography-mass spectrometry specific ion monitoring (GC-MS SIM) analysis following liquid-liquid extraction. No other drugs or medications, including fentanyl, were detected. The acetyl fentanyl peripheral blood concentration was quantified at 260 ng/mL compared with the central blood concentration of 250 ng/mL. The liver concentration was 1,000 ng/kg, the vitreous was 240 ng/mL and the urine was 2,600 ng/mL. The cause of death was certified due to acute acetyl fentanyl intoxication, and the manner of death was certified as an accident.
Language: en
LA - en SN - 0146-4760 UR - http://dx.doi.org/10.1093/jat/bkv043 ID - ref1 ER -