TY - JOUR PY - 2015// TI - Specific attentional disorders and freezing of gait in Parkinson's disease JO - Journal of Parkinson's disease A1 - Tard, Céline A1 - Delval, Arnaud A1 - Duhamel, Alain A1 - Moreau, Caroline A1 - Devos, David A1 - Defebvre, Luc A1 - Dujardin, Kathy SP - 379 EP - 387 VL - 5 IS - 2 N2 - BACKGROUND: Due to its high prevalence in dual-task paradigms, freezing of gait in Parkinson's disease is thought to be associated with dysexecutive syndrome and attentional disorders. However, the role of specific attentional disorders in patients with freezing of gait is still unclear.

OBJECTIVE: Here, we sought to specifically determine which basic attentional modalities are impaired in patients with freezing of gait.

METHODS: Seventy-eight parkinsonian patients performed a computer-controlled reaction-time paradigm designed to measure the different attentional subcomponents, controlled for visuospatial processing and motor participation.

RESULTS: The freezer (n = 42) and non-freezer (n = 36) groups were matched for age, educational level, MMSE and MDRS. There were no intergroup differences in simple reaction times, whereas choice reaction times were higher in the freezer group than in the non-freezer group for divided attention (p = 0.023).

CONCLUSIONS: At equivalent levels of overall cognitive efficiency, freezer patients showed a greater slowdown than non-freezer patients with a specific impairment in divided attention.

Language: en

LA - en SN - 1877-7171 UR - http://dx.doi.org/10.3233/JPD-140498 ID - ref1 ER -