TY  - JOUR
PY  - 2015//
TI  - A Meta-Analysis of the Reliability of the History in Suspected Poisoning
JO  - Journal of emergency medicine
A1  - Camilleri, Robert
SP  - 679
EP  - 684
VL  - 48
IS  - 6
N2  - BACKGROUND: Management of acute poisoning depends on the reliability of history of the poisoning event. <br><br>OBJECTIVE: The objective of this study was to perform a meta-analysis from published data to determine summary measures of reliability of history in suspected acute poisoning. <br><br>METHOD: Relevant studies were selected from a search on the Medline database to perform a meta-analysis to calculate pooled estimates of κ statistic for agreement between history of poisoning and laboratory diagnosis. <br><br>RESULTS: A total of seven articles were included in the meta-analysis. The κ statistic varied from 0.35 (95% confidence interval [CI] 0.135-0.558) for 3,4-methylenedioxy-N-methylamphetamine (MDMA, also known as ecstasy) to 0.69 (95% CI 0.648-0.733) for paracetamol. <br><br>CONCLUSIONS: A history of paracetamol ingestion is moderately reliable, and further evaluation is required to make a clinical diagnosis of acute poisoning with street drugs.<p /> <p>Language: en</p>
LA  - en
SN  - 0736-4679
UR  - http://dx.doi.org/10.1016/j.jemermed.2014.12.067
ID  - ref1
ER  -