TY  - JOUR
PY  - 2014//
TI  - Cortisol reactivity to social stress as a mediator of early adversity on risk and adaptive outcomes
JO  - Child development
A1  - Conradt, Elisabeth
A1  - Abar, Beau W.
A1  - Lester, Barry M.
A1  - Lagasse, Linda L.
A1  - Shankaran, Seetha
A1  - Bada, Henrietta
A1  - Bauer, Charles R.
A1  - Whitaker, Toni M.
A1  - Hammond, Jane A.
SP  - 2279
EP  - 2298
VL  - 85
IS  - 6
N2  - Children chronically exposed to stress early in life are at increased risk for maladaptive outcomes, though the physiological mechanisms driving these effects are unknown. Cortisol reactivity was tested as a mediator of the relation between prenatal substance exposure and/or early adversity on adaptive and maladaptive outcomes. Data were drawn from a prospective longitudinal study of prenatal substance exposure (N = 860). Cortisol reactivity was assessed at age 11. Among African Americans, prenatal substance exposure exerted an indirect effect through early adversity and cortisol reactivity to predict externalizing behavior, delinquency, and a positive student--teacher relationship at age 11. Decreased cortisol reactivity was related to maladaptive outcomes, and increased cortisol reactivity predicted better executive functioning and a more positive student--teacher relationship.<p />  <p>Language: en</p>
LA  - en
SN  - 0009-3920
UR  - http://dx.doi.org/10.1111/cdev.12316
ID  - ref1
ER  -