TY  - JOUR
PY  - 2014//
TI  - Acute 5-(2-aminopropyl)benzofuran (5-apb) intoxication and fatality: a case report with postmortem concentrations
JO  - Journal of analytical toxicology
A1  - McIntyre, Iain M.
A1  - Gary, Ray D.
A1  - Trochta, Amber
A1  - Stolberg, Susan
A1  - Stabley, Robert
SP  - 156
EP  - 159
VL  - 39
IS  - 2
N2  - A 20-year-old man, a college student, became unresponsive in front of his girlfriend. He was known to consume alcohol and take an unknown drug at some point while in attendance at a local music festival earlier in the day/evening. Upon arrival of emergency personnel, he was noted to be asystolic and apneic. Despite aggressive medical intervention by emergency personnel and at a local hospital emergency room, he was pronounced deceased within 1.25 h of initial medical attention. Postmortem blood initially screened positive for methamphetamine by ELISA. An alkaline drug screen detected 5-(2-aminopropyl)benzofuran (5-APB) which was subsequently confirmed and quantified by a specific GC-MS SIM analysis following solid-phase extraction. Concentrations were determined in the peripheral blood (2.5 mg/L), central blood (2.9 mg/L), liver (16 mg/kg), vitreous (1.3 mg/L), urine (23 mg/L) and gastric contents (6 mg). No other common amphetamine-like compound was detected, although 5-(2-aminopropyl)-2,3-dihydrobenzofuran (5-APDB) was presumptively identified in both peripheral blood and urine. Alcohol, the only other drug identified, was confirmed at a concentration of 0.02% (w/v).<p />  <p>Language: en</p>
LA  - en
SN  - 0146-4760
UR  - http://dx.doi.org/10.1093/jat/bku131
ID  - ref1
ER  -