TY  - JOUR
PY  - 2014//
TI  - Ischemia/reperfusion injury and its consequences on immunity and inflammation
JO  - Curr Transplant Rep
A1  - Slegtenhorst, Bendix R.
A1  - Dor, Frank Jmf
A1  - Rodriguez, Hector
A1  - Voskuil, Floris J.
A1  - Tullius, Stefan G.
SP  - 147
EP  - 154
VL  - 1
IS  - 3
N2  - Ischemia/reperfusion injury (IRI), an inherent component of transplantation, affects organ quality and transplant outcomes. Although the complexity of the pathophysiology is recognized, detailed mechanisms remain unclear, and strategies preventing the consequences of IRI have been challenging. Of critical significance appears the link between IRI, the initiation of innate immune responses, and the (potential) augmentation of adaptive immunity. An improved understanding of those complex mechanisms and interactions may pave the way for more effective treatment strategies.<p />  <p>Language: en</p>
LA  - en
SN  - 2196-3029
UR  - http://dx.doi.org/10.1007/s40472-014-0017-6
ID  - ref1
ER  -