TY  - JOUR
PY  - 1987//
TI  - Mental outcome in West syndrome: prognostic value of some clinical factors
JO  - Journal of mental deficiency research
A1  - Favatà, I.
A1  - Leuzzi, V.
A1  - Curatolo, P.
SP  - 9
EP  - 15
VL  - 31 ( Pt 1)
IS  - 
N2  - Fifty-eight cases of West syndrome (eight idiopathic, 50 secondary) have been followed-up for a mean period of 5 years 5 months. The relationship has been studied between intellectual status at the final follow-up and the following variables: etiology, age of onset, neurological examination and developmental assessment at the onset, CT scan findings, short-term effect of ACTH treatment, and age of acquiring four developmental milestones (sitting unsupported, walking unsupported, uttering the first specific word and using a sentence of two words). Developmental and/or neurological abnormalities before the onset of the spasms, symptomatic etiology and abnormal CT findings are associated with a low IQ at the final follow-up. The age for sitting unsupported and for walking unsupported has proved to be not predictive of intellectual outcome, but the speech development data have shown a highly significant relationship with intellectual development. Early identification of the children with mental retardation has turned out to be superior to prediction of normal mental outcome.<p /> <p>Language: en</p>
LA  - en
SN  - 0022-264X
UR  - http://dx.doi.org/
ID  - ref1
ER  -