TY - JOUR PY - 1989// TI - Psychotoxic effects of ofloxacin JO - Pharmacopsychiatry A1 - Zaudig, M. A1 - von Bose, M. A1 - Weber, M. M. A1 - Bremer, D. A1 - Zieglgänsberger, W. SP - 11 EP - 15 VL - 22 IS - 1 N2 - Two cases of organic psychosis, induced by the new chemotherapeutic agent ofloxacin (Tarivid), are described. According to DSM-III-R and ICD 10 (draft, 1987) both cases present as different, yet well-defined diagnostic categories: the new diagnostic systems appear to be superior and markedly more differentiated than ICD-9, since they provide a more exact and comprehensive description and more specific diagnostic allocation, especially in substance-specific syndromes. The possible involvement of GABAergic and monaminergic mechanisms in this psychotic symptomatology and their relationship to hypersynchronous states are discussed in detail.

Language: en

LA - en SN - 0176-3679 UR - http://dx.doi.org/10.1055/s-2007-1014570 ID - ref1 ER -