TY - JOUR PY - 1989// TI - Toxicity of antidepressants in overdose JO - International journal of clinical pharmacology research A1 - Leonard, B. E. SP - 101 EP - 110 VL - 9 IS - 2 N2 - The paper is concerned with the greater risk of self-poisoning and successful suicide in the use of the older tricyclic antidepressant drugs by the depressed patient. It defines the factors which must be taken into account when undertaking a cost-benefit analysis of an antidepressant drug in addition to its efficacy, and concludes that there would appear to be every reason for considering the replacement of the older tricyclic antidepressants with newer non-tricyclic drugs in the first line of treatment of depression.
Language: en
LA - en SN - 0251-1649 UR - http://dx.doi.org/ ID - ref1 ER -