TY  - JOUR
PY  - 1988//
TI  - Subacute acetaminophen overdose after incremental dosing
JO  - Journal of emergency medicine
A1  - Mathis, R. D.
A1  - Walker, J. S.
A1  - Kuhns, D. W.
SP  - 37
EP  - 40
VL  - 6
IS  - 1
N2  - A case of acetaminophen poisoning following the ingestion of 26 g of acetaminophen by incremental dosing over a 25-h period is reported. At presentation, seven h after the last ingestion, the patient experienced hematemesis, the acetaminophen level was 150 micrograms/mL, and the SGOT was normal. The patient recovered uneventfully following N-acetylcysteine therapy. A review of the pharmacology and toxicity of acetaminophen is discussed. The case illustrates the problems of judging hepatotoxic potential in a multiple-dose acetaminophen ingestion and describes the successful use of N-acetylcysteine in a patient with a "subacute" acetaminophen overdose.<p /> <p>Language: en</p>
LA  - en
SN  - 0736-4679
UR  - http://dx.doi.org/
ID  - ref1
ER  -