TY - JOUR PY - 2014// TI - Can carbon monoxide-poisoned victims be organ donors? JO - Medical gas research A1 - Fujisaki, Noritomo A1 - Nakao, Atsunori A1 - Osako, Takaaki A1 - Nishimura, Takeshi A1 - Yamada, Taihei A1 - Kohama, Keisuke A1 - Sakata, Hiroyuki A1 - Ishikawa-Aoyama, Michiko A1 - Kotani, Joji SP - 13 EP - 13 VL - 4 IS - N2 - The increasing demand for organ allografts to treat end-stage organ failure has driven changes in traditional donor criteria. Patients who have succumbed to carbon monoxide (CO) poisoning, a common cause of toxicological mortality, are usually rejected as organ donors. To fulfill the increasing demand, selection criteria must be expanded to include CO-poisoned donors. However, the use of allografts exposed to high CO concentrations is still under debate. Basic research and literature review data suggest that patients with brain death caused by CO poisoning should be considered appropriate organ donors. Accepting organs from CO-poisoned victims could increase the number of potential donors and lower the death rate of patients on the waiting lists. This review and reported cases may increase awareness among emergency department physicians, as well as transplant teams, that patients dying of CO exposure may be acceptable organ donors.
Language: en
LA - en SN - 2045-9912 UR - http://dx.doi.org/10.1186/2045-9912-4-13 ID - ref1 ER -