TY  - JOUR
PY  - 1986//
TI  - Psychotropic properties of corticotropin and its analogs
JO  - Probl Endokrinol (Mosk)
A1  - Tikhomirov, S. M.
A1  - Bakharev, V. D.
SP  - 46
EP  - 49
VL  - 32
IS  - 1
N2  - The authors presented evidence for the effect of 6 analogues of ACTN4-10 on teaching of albino rats in a labyrinth with negative electrocutaneous reinforcement. Sixteen series of experiments on 192 rats demonstrated a positive effect of corticotropin fragments on memory processes. The activating ACTH fragment effect was shown in recording the background and bioelectrically induced rabbit brain activity in response to a photo-flash in 36 experiments on 18 animals. Three groups of 30 patients with alcohol withdrawal syndrome, posttraumatic craniocerebral effect and schizophrenia received injections of corticotropin as a therapeutic agent. A high efficacy of corticotropin in the treatment of the alcohol withdrawal syndrome and after effect of craniocerebral injury and a low efficacy and sometimes aggravation of symptoms in schizophrenia patients were shown.<p /> <p>Language: ru</p>
LA  - ru
SN  - 0375-9660
UR  - http://dx.doi.org/
ID  - ref1
ER  -