TY - JOUR PY - 1985// TI - Benzodiazepine antagonist (RO 15-1788) in ethanol intoxication: a pilot study JO - European neurology A1 - Scollo-Lavizzari, G. A1 - Matthis, H. SP - 352 EP - 354 VL - 24 IS - 5 N2 - In 1983, we reported on the excellent efficacy of the benzodiazepine antagonist RO 15-1788 in cases of acute intoxication with diazepam in intensive care medicine. Upon observing a positive effect in a patient who had taken alcohol as well as diazepam a study aiming at establishing the beneficial effect of RO 15-1788 in alcoholic intoxication was started. In the meantime, we discovered a significant amelioration of the cerebral disturbance in patients suffering from hepatic coma by the same benzodiazepine antagonist. The preliminary results of a multicenter study reflecting the beneficial effect of RO 15-1788 in cases of alcohol intoxication will be presented.

Language: en

LA - en SN - 0014-3022 UR - http://dx.doi.org/ ID - ref1 ER -