TY - JOUR PY - 2014// TI - Cognitive impairment in earthquake brain injury treated with comprehensive program of acupuncture and rehabilitation: a randomized controlled trial JO - Zhongguo Zhen Jiu A1 - Zhou, Jian-Wei A1 - Zhang, An-Ren A1 - Qiu, Ling A1 - Huang, Shu A1 - Wang, Wen-Chun A1 - Hu, Yong-He A1 - Zhang, Zhao A1 - Xie, Hui-Jun A1 - Zhao, Jing-Jing A1 - Zhai, Jia-Li A1 - Jiang, Yue A1 - Tian, Tian A1 - Liu, Di A1 - Zheng, Xu A1 - Wang, Min SP - 105 EP - 109 VL - 34 IS - 2 N2 - OBJECTIVE: To explore the comprehensive program of integrated Chinese and western medicine in the treatment of cognitive impairment in earthquake brain injury.

METHODS: The multi-central randomized controlled trial was adopted. The qualified subjects were randomized into an acupuncture + rehabilitation group (38 cases) and a rehabilitation group (35 cases). In the acupuncture + rehabilitation group, acupuncture, hyperbaric oxygen (HBO) and cognitive rehabilitation training were combined as the comprehensive program of integrated Chinese and western medicine in the treatment. In the rehabilitation group, HBO and cognitive rehabilitation training were adopted. The efficacy and safety were assessed.

RESULTS: (1) After treatment of 2 months, the intelligent state, cognitive function and activity of daily life of patients were improved in the both groups (all P < 0.01). (2) After treatment of 2 months, the score of MMSE and the score of activity of daily life were (24.11 +/- 4.08) and (75.45 +/- 13.95) in the acupuncture + rehabilitation group, which were more significant as compared with (17.05 +/- 43.84), (66.06 +/- 12.75) in the rehabilitation group, respectively (both P < 0.01). In 6-month follow-up visit after treatment, the cognitive function and activity of daily life were improved continuously in the acupuncture + rehabilitation group, which was more significant as compared with the rehabilitation group (P < 0.01, P < 0.05).

CONCLUSION: The integrated Chinese and western medicine of acupuncture, HBO and cognitive rehabilitation training is safe and effective in the treatment of cognitive impairment in earthquake brain injury. The therapeutic effect is more advantageous as compared with the simple rehabilitation program of western medicine.

Language: zh

LA - zh SN - 0255-2930 UR - http://dx.doi.org/ ID - ref1 ER -