TY - JOUR PY - 1980// TI - Disseminated intravascular coagulation following cranial trauma. Case report JO - Journal of neurosurgery A1 - Clark, J. A. A1 - Finelli, R. E. A1 - Netsky, M. G. SP - 266 EP - 269 VL - 52 IS - 2 N2 - Cranial and spinal trauma resulted in disseminated intravascular coagulation (DIC) in a 78-year-old man, causing widespread bleeding and incoagulable blood. Traumatized brain tissue was found in the lumina of dural venous sinuses. The mechanisms of DIC are reviewed. It is suggested that intravascular release of potent cerebral thromboplastin contributed to the severity of DIC in this patient, by causing activation of the extrinsic clotting system. Intrasinus brain tissue in cases of human trauma has not previously been reported.

Language: en

LA - en SN - 0022-3085 UR - http://dx.doi.org/10.3171/jns.1980.52.2.0266 ID - ref1 ER -