TY  - JOUR
PY  - 1984//
TI  - Oxprenolol plus ethanol causes no central nervous system depression--a comparison with lorazepam plus ethanol
JO  - South African medical journal SAMJ
A1  - Aucamp, A. K.
A1  - Weis, O. F.
A1  - Müller, F. O.
A1  - Gill, C. E.
A1  - Malan, J.
SP  - 445
EP  - 446
VL  - 66
IS  - 12
N2  - Oxprenolol, a fat-soluble beta-adrenergic blocker, promoted as an anxiolytic agent to alleviate peripheral symptoms associated with anxiety, and lorazepam, a 1,4-benzodiazepine anxiolytic drug, may both depress central nervous system (CNS) function. It is generally accepted that ethanol, when concurrently ingested, potentiates the CNS-depressant effects of drugs. The effects on CNS function of oxprenolol, lorazepam and placebo alone and in combination with ethanol were determined by a Leeds Psychomotor Tester and we concluded that oxprenolol in combination with ethanol is less hazardous to people operating power tools/machines or driving motor vehicles than the combination of lorazepam with ethanol.<p /> <p>Language: en</p>
LA  - en
SN  - 0038-2469
UR  - http://dx.doi.org/
ID  - ref1
ER  -