TY  - JOUR
PY  - 2012//
TI  - Effects of neurosurgical treatment and severity of head injury on cognitive functioning, general health and incidence of mental disorders in patients with traumatic brain injury
JO  - Archives of trauma research
A1  - Rezaei, Sajjad
A1  - Asgari, Karim
A1  - Yousefzadeh, Shahrokh
A1  - Moosavi, Heshmat-Allah
A1  - Kazemnejad, Ehsan
SP  - 93
EP  - 100
VL  - 1
IS  - 3
N2  - BACKGROUND: Neurosurgical treatment and the severity of head injury (HI) can have remarkable effect on patients' neuropsychiatric outcomes. OBJECTIVES: This research aimed to study the effect of these factors on cognitive functioning, general health and incidence of mental disorders in patients with a traumatic brain injury (TBI). PATIENTS AND METHODS: In this descriptive, longitudinal study, 206 TBI patients entered the study by consecutive sampling; they were then compared according to neurosurgery status and severity of their HI. Both groups underwent neurosurgical and psychological examinations. The mini mental state examination (MMSE) and general health questionnaire-28 items (GHQ-28) were administered to the study participants. At follow-up, four months later, the groups underwent a structured clinical interview by a psychiatrist based on the diagnostic and statistical manual of mental disorders, fourth edition (DSM-IV) diagnostic criteria regarding the presence of mental disorders. RESULTS: Analysis of covariance (ANCOVA) and multivariate analysis of covariance (MANCOVA) were performed and adjusted for the effect of confounding variables (age, gender, Glasgow outcome scale (GOS) , and level of education). The severity of HI had the most significant effect for the following variables; cognitive functioning and physical symptoms (P < 0.05). The effect of the neurosurgical treatment factor was not significant; however, the interaction effect of the two variables on social dysfunction, and total score of the GHQ-28 questionnaire appeared to be significant (P < 0.05). Fisher's exact test indicated that after a four month follow-up period, no significant differences were seen between the two groups (with or without neurosurgery) in the incidence of mental disorders, while χ(2) Test showed that having a more severe HI is significantly correlated with the incidence of mental disorders (P < 0.01). CONCLUSIONS: The implications of this study should be discussed with an emphasis on negative, effective factors on the cognitive - behavioral and neuropsychiatric outcomes of a TBI.<p /> <p>Language: en</p>
LA  - en
SN  - 2251-953X
UR  - http://dx.doi.org/10.5812/atr.6546
ID  - ref1
ER  -