TY - JOUR PY - 2013// TI - Independent hypothalamic circuits for social and predator fear JO - Nature neuroscience A1 - Gross, Cornelius T. A1 - Ragozzino, Davide A1 - Canteras, Newton S. A1 - Grinevich, Valery A1 - Illarionova, Anna A1 - Murana, Emanuele A1 - Krzywkowski, Piotr A1 - Mattucci, Camilla A1 - Silva, Bianca A. SP - 1731 EP - 1733 VL - 16 IS - 12 N2 - The neural circuits mediating fear to naturalistic threats are poorly understood. We found that functionally independent populations of neurons in the ventromedial hypothalamus (VMH), a region that has been implicated in feeding, sex and aggression, are essential for predator and social fear in mice. Our results establish a critical role for VMH in fear and have implications for selective intervention in pathological fear in humans.

Language: en

LA - en SN - 1097-6256 UR - http://dx.doi.org/10.1038/nn.3573 ID - ref1 ER -